Voice all of a sudden will not register through headset

[Ngwelch33]

Hey guys.

So my wife had just bought me a Turtle Beach z22 headset for my gaming habits. I had plugged them in, adjusted the input/output settings on the voice program I was using, Ventrilo, and they worked perfect. Everything was amazing. UNTIL, I had unplugged my usb and 3.5mm jack to let my wife listen to the music I was listening too. Since I unplugged them from my computer, they have not worked since. They work fine on Skype, through phone calls, everything but Ventrilo now. I've changed the settings 100 times and re-installed to no avail. Does anyone have an idea on how I can fix this?

Thanks in advance guys